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Across many studies of mammals, from the smallest rodents all the way to us humans, the data suggests that we are profoundly shaped by our social environment and that we suffer greatly when our social bonds are threatened or severed. When this happens in childhood it can lead to long-term health and educational problems. We may not like the fact that we are wired such that our well-being depends on our connections with others, but the facts are the facts. - Matthew Lieberman, neuroscientist and author of Social: Why Our Brains are Wired to Connect 
Neuroscience is confirming that our nervous systems want us to connect with other human beings. A good example of this is mirror neurons, which are located throughout the brain and help us read other people's feelings and actions. They may be the neurological underpinnings of empathy - when two people are in conversation they are stimulating each other's mirror neuron system. Not only will this lead to movement in similar muscles of the face (so the expressions are similar) but it also allows each to feel what the other is feeling. This is an automatic, moment to moment resonance that connects us. There have been studies that look at emotions in human beings such as disgust, shame, happiness, where the exact same areas of the brain light up in the listener who is reading the feelings of the person talking. We are, literally, hardwired to connect. 
I believe that one of the seminal studies that supports a relational neurobiology is something called SPOT (Social Pain Overlap Theory.) A group of researchers at UCLA, looked at the overlap between social pain and physical pain. They designed a benign computerized experiment that gradually excluded people from a multi-player game. What they found was the area that lit up in the brain for that kind of social rejection—the anterior cingulate—was the exact same area that lights up for the distress of physical pain. So the distress of social pain is biologically identical to the distress of physical pain. Most people in our culture understand that physical pain is a major stressor, but we often reject the idea of social pain. 
Yes, being pushed out of social relationships and into isolation has health ramifications. In fact, there was a book done by health advocate Dr. Dean Ornish, called Love and Survival. There has been study after study done on the positive impact of loving relationships. What he had said at the time in that book was that if we had a drug that did for our health what love does, it would far outsell anything that has ever been made. The efficacy is that potent. But we downplay the importance of love and connection in a culture based on the success of “the rugged individual.” People in our culture need to understand that healthy connection can reduce pain on all levels. Yes, we are a culture that downplays love and connection and holds tough discipline in high esteem. We train our children by use of pain; either physical pain or social pain. Which is really quite a paradox as children don't learn well through pain. The fear created by being hit or feeling the threat of disconnection from a primary attachment figure triggers the fight or flight response. By it's very nature, this bypasses the rational mind and puts people in attack mode, thereby inhibiting learning.
We form our beliefs for a variety of subjective, personal, emotional, and psychological reasons in the context of environments created by family, friends, colleagues, culture, and society at large; after forming our beliefs we then defend, justify, and rationalize them with a host of intellectual reasons, cogent arguments, and rational explanations... Once beliefs are formed the brain begins to look for and find confirmatory evidence in support of those beliefs, which adds an emotional boost of further confidence in the beliefs and thereby accelerates the process of reinforcing them, and round and round the process goes in a positive feedback loop of belief confirmation.
Dr. Shermer outlines the numerous cognitive tools our brains engage to reinforce our beliefs as truths and to insure that we are always right.